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Peptide record

TPDB25633

Antibacterial Antifungal Hemolysis Toxicity standard
64 amino acids
Basic Information
3D PDB MODEL
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TPDB25633
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 64-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
SISCKAGRVGCFASCQVQNCATGYCRGSTCVCSRCGKGTTPFNKFKIWNQLRVLVQKMVDEERA
Physicochemical Analysis
C296H482N92O88S9
H
C
7026.19
9.00
10
3
20
+7
9.24
-0.167
57.81
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
7490
106.60
25
Residue Composition
number
4
A
5
R
3
N
1
D
8
C
2
E
4
Q
6
G
0
H
2
I
2
L
5
K
1
M
3
F
1
P
5
S
4
T
1
W
1
Y
6
V
Amino Acid Distribution
A: 4 R: 5 N: 3 D: 1 C: 8 E: 2 Q: 4 G: 6 H: 0 I: 2 L: 2 K: 5 M: 1 F: 3 P: 1 S: 5 T: 4 W: 1 Y: 1 V: 6
Chemical Descriptors
64
C296H482N92O88S9
7026.19
9.00
+7
9.24
-0.167
Evidence Records 3 records
Evidence 1 Activity

Activity

35% Hemolysis
Toxicity
1 µg/mL
Hemolytic Cytotoxic
35% Hemolysis | 1 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo. | Mar Drugs | 2011
Evidence 2 Activity

Activity

76% Hemolysis
Toxicity
10 µg/mL
Hemolytic Cytotoxic
76% Hemolysis | 10 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Inducible ASABF-type antimicrobial peptide from the sponge Suberites domuncula: microbicidal and hemolytic activity in vitro and toxic effect on molluscs in vivo. | Mar Drugs | 2011
Evidence 3 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis