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Peptide record

TPDB25616

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB25616
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
SHHRPRLFHRHRH
Physicochemical Analysis
C77H117N35O15
ANDCEQGIKMTWYV
H
1773.00
12.88
9
0
2
+4
6.93
-2.292
30.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
5
H
0
I
1
L
0
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 5 I: 0 L: 1 K: 0 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C77H117N35O15
1773.00
12.88
+4
6.93
-2.292
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>32 µg/mL
Cytotoxic
50% Cytotoxicity | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019