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Peptide record

TPDB25613

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB25613
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Sequence
SHHRHFRSHQCR
Physicochemical Analysis
C65H98N30O16S1
ANDEGILKMPTWYV
H
1587.74
12.10
7
0
1
+3
5.74
-2.175
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
0
A
3
R
0
N
0
D
1
C
0
E
1
Q
0
G
4
H
0
I
0
L
0
K
0
M
1
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 4 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C65H98N30O16S1
1587.74
12.10
+3
5.74
-2.175
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>32 µg/mL
Cytotoxic
50% Cytotoxicity | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019