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Peptide record

TPDB25590

Antibacterial Antifungal Toxicity modified_plain modified
31 amino acids
Basic Information
3D PDB MODEL
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TPDB25590
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 31-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
SGHSSVFGQHESGSGHSSAYSQHGSGSGHFX
Physicochemical Analysis
C124H172N42O46
RNDCILKMPTW
S
2986.98
6.60
5
1
5
-1
6.05
-0.871
12.58
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
49.88
13
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
2
Q
7
G
5
H
0
I
0
L
0
K
0
M
2
F
0
P
10
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 7 H: 5 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 10 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
31
C124H172N42O46
2986.98
6.60
-1
6.05
-0.871
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>32 µg/mL
Cytotoxic
50% Cytotoxicity | >32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Cationic Intrinsically Disordered Antimicrobial Peptides (CIDAMPs) Represent a New Paradigm of Innate Defense with a Potential for Novel Anti-Infectives. | Sci Rep | 2019