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Peptide record

TPDB25557

Antibacterial Antiviral Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB25557
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
SEETKENEGFTVTAEGK
Physicochemical Analysis
C77H122N20O33
RDCQHILMPWY
E
1855.93
4.08
2
5
3
-3
11.84
-1.394
22.94
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
5
E
0
Q
2
G
0
H
0
I
0
L
2
K
0
M
1
F
0
P
1
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 5 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 1 P: 0 S: 1 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C77H122N20O33
1855.93
4.08
-3
11.84
-1.394
Evidence Records 4 records
Evidence 1 Activity

Activity

<10% Cell death
Toxicity
100 µg/mL
Cytotoxic
<10% Cell death | 100 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Antiviral Activity of Synthetic Peptides Derived from Physiological Proteins. | Intervirology | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 3 Activity

Activity

1.12% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
1.12% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Peptide Found in Human Serum, Derived from the C-Terminus of Albumin, Shows Antifungal Activity In Vitro and In Vivo. | Microorganisms | 2020
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.30654366]<10% cytotoxicity against Vero cells at the concentration of 100µg/ mL.

Source & Reference

NA
DRAMP
Intervirology. 2018 61(4):166-173.