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Peptide record

TPDB25522

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB25522
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept AI4AVP APD_complete APD_hemolytic HemoPI Hemolytic2 ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, iACP-DRLF, and other sources, with an available 3D structural model.
Sequence
SAISCGETCFKFKCYTPRCSCSYPVCK
Physicochemical Analysis
C129H199N33O38S6
NDQHLMW
C
3012.56
8.30
4
1
7
+3
1.52
0.022
28.89
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
3355
111.37
14
Residue Composition
number
1
A
1
R
0
N
0
D
6
C
1
E
0
Q
1
G
0
H
1
I
0
L
3
K
0
M
2
F
2
P
4
S
2
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 3 M: 0 F: 2 P: 2 S: 4 T: 2 W: 0 Y: 2 V: 1
Chemical Descriptors
27
C129H199N33O38S6
3012.56
8.30
+3
1.52
0.022
Evidence Records 3 records
Evidence 1 Activity

Activity

% Hemolysis
Hemolysis
10 35 %
[Ref:16488428]10% hemolytic activity at 1.0µM and 35% hemolytic activity at 1.5µM against human type A red blood cells

Target

human type A red blood cells

Source & Reference

APD_complete APD_hemolytic
DRAMP4
Biochem J. 2006 Nov 15 400(1):1-12.##J Mol Biol. 2006 Apr 14 357(5):1522-1535.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref:16488428]10% hemolytic activity at 1.0µM and 35% hemolytic activity at 1.5µM against human type A red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Biochem J. 2006 Nov 15 400(1):1-12.##J Mol Biol. 2006 Apr 14 357(5):1522-1535.
Evidence 3 Hemolysis

Activity

10 35 %
% Hemolysis
[Ref:16488428]10% hemolytic activity at 1.0µM and 35% hemolytic activity at 1.5µM against human type A red blood cells
Hemolysis

Target

human type A red blood cells

Source & Reference

APD_complete APD_hemolytic HemoPI
Biochem J. 2006 Nov 15 400(1):1-12.##J Mol Biol. 2006 Apr 14 357(5):1522-1535.
DRAMP4
APD_complete APD_hemolytic