Peptide record

TPDB25497

Antibacterial Toxicity modified_plain modified
6 amino acids
Basic Information
3D PDB MODEL
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TPDB25497
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 6-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RXXRFR
Physicochemical Analysis
C27H47N13O5
ANDCEQGHILKMPSTWYV
R
633.75
12.70
3
0
1
+3
1.30
-1.783
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C27H47N13O5
633.75
12.70
+3
1.30
-1.783
Evidence Records 1 records
Evidence 1 Activity

Activity

6.1% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
6.1% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of arginine- and tryptophan-rich hexapeptides: the effects of aromatic clusters, D-amino acid substitution and cyclization | J Pept Res | 2004