Back to search

Peptide record

TPDB25489

Antibacterial Toxicity modified_plain modified
7 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB25489
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 7-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RXWKXXK
Physicochemical Analysis
C29H48N10O5
ANDCEQGHILMFPSTYV
K
616.76
11.64
3
0
1
+3
0.94
-1.886
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
891.75
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C29H48N10O5
616.76
11.64
+3
0.94
-1.886
Evidence Records 2 records
Evidence 1 Activity

Activity

4.3% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
4.3% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of lysine-to-arginine substitution on antimicrobial activity of cationic stapled heptapeptides. | Arch Pharm Res | 2018
Evidence 2 Activity

Activity

1.5% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.5% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Effects of lysine-to-arginine substitution on antimicrobial activity of cationic stapled heptapeptides. | Arch Pharm Res | 2018