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Peptide record

TPDB25480

Antibacterial Antifungal Toxicity modified_plain modified
22 amino acids
Basic Information
3D PDB MODEL
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TPDB25480
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 22-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
RXPGRTRQIGTIFGPRIKXRSW
Physicochemical Analysis
C106H176N38O25
ANDCEHLMYV
R
2382.80
13.00
6
0
5
+6
3.05
-0.959
53.18
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
230.82
4
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
1
Q
3
G
0
H
3
I
0
L
1
K
0
M
1
F
2
P
1
S
2
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 3 L: 0 K: 1 M: 0 F: 1 P: 2 S: 1 T: 2 W: 1 Y: 0 V: 0
Chemical Descriptors
22
C106H176N38O25
2382.80
13.00
+6
3.05
-0.959
Evidence Records 2 records
Evidence 1 Activity

Activity

70% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
70% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
N-terminal fatty acylation of peptides spanning the cationic C-terminal segment of bovine ?-defensin-2 results in salt-resistant antibacterial activity. | Biophys Chem | 2015
Evidence 2 Activity

Activity

20% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
20% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
N-terminal fatty acylation of peptides spanning the cationic C-terminal segment of bovine ?-defensin-2 results in salt-resistant antibacterial activity. | Biophys Chem | 2015