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Peptide record

TPDB25467

Antibacterial Anticancer Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB25467
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RWWWRR
Physicochemical Analysis
C51H68N18O7
ANDCEQGHILKMFPSTYV
RW
1045.22
12.70
3
0
3
+3
-3.12
-2.700
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
16500
1578.62
0
Residue Composition
number
0
A
3
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
6
C51H68N18O7
1045.22
12.70
+3
-3.12
-2.700
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The pharmacophore of short cationic antibacterial peptides. | J Med Chem | 2003
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybrid Antimicrobial Peptide Targeting Staphylococcus aureu s and Displaying Anti-infective Activity in a Murine Model. | Front Microbiol | 2020