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Peptide record

TPDB25442

Antibacterial Antifungal Antiviral Toxicity standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB25442
Antibacterial Antifungal Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb DRAMP dbAMP
standard
No
A 4-aa standard natural multi-activity (Antibacterial, Antifungal, Antiviral, and other sources) peptide sequence curated from Peptipedia, CAFPdb, DRAMP, and other sources, with an available 3D structural model.
Sequence
RWRW
Physicochemical Analysis
C34H46N12O5
ANDCEQGHILKMFPSTYV
RW
702.82
12.40
2
0
2
+2
-2.08
-2.700
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
1565.13
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
4
C34H46N12O5
702.82
12.40
+2
-2.08
-2.700
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
The pharmacophore of short cationic antibacterial peptides. | J Med Chem | 2003
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
3700 µM
Hemolytic Cytotoxic
50% Hemolysis | 3700 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Length effects in antimicrobial peptides of the (RW)n series | Antimicrob Agents Chemother | 2007