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Peptide record

TPDB25438

Antibacterial Anticancer Antifungal Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB25438
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RWRIRIRWL
Physicochemical Analysis
C64H103N23O10
ANDCEQGHKMFPSTYV
R
1354.67
12.88
4
0
5
+4
-1.64
-0.778
130.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
812.01
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
9
C64H103N23O10
1354.67
12.88
+4
-1.64
-0.778
Evidence Records 3 records
Evidence 1 Activity

Activity

3% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
3% Hemolysis | 64 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterization of simplified nonapeptides with broad-spectrum antimicrobial activities as potential food preservatives, and their antibacterial mechanism. | Food Funct | 2023
Evidence 2 Activity

Activity

12% Cell death
Toxicity
32 µM
Cytotoxic
12% Cell death | 32 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Characterization of simplified nonapeptides with broad-spectrum antimicrobial activities as potential food preservatives, and their antibacterial mechanism. | Food Funct | 2023
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Intestinal Porcine Epithelial Cells IPEC-J2

Target

Intestinal Porcine Epithelial Cells IPEC-J2

Source & Reference

NA
DBAASP
Characterization of simplified nonapeptides with broad-spectrum antimicrobial activities as potential food preservatives, and their antibacterial mechanism. | Food Funct | 2023