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Peptide record

TPDB25434

Antibacterial Anticancer Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB25434
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RWNGRIIKGFYNLVKIWKDLKG
Physicochemical Analysis
C129H202N36O28
ACEQHMPST
K
2705.25
11.02
6
1
10
+5
-0.07
-0.514
101.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12490
461.70
3
Residue Composition
number
0
A
2
R
2
N
1
D
0
C
0
E
0
Q
3
G
0
H
3
I
2
L
4
K
0
M
1
F
0
P
0
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 3 L: 2 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
22
C129H202N36O28
2705.25
11.02
+5
-0.07
-0.514
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
89±6 µM
Hemolytic Cytotoxic
50% Hemolysis | 89±6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing Anticancer Peptides by Constructive Machine Learning. | ChemMedChem | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes：50% Hemolysis=89±6 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ChemMedChem. 2018 Jul 6 13(13):1300-1302.