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Peptide record

TPDB25418

Antibacterial Antifungal Toxicity modified_plain modified
21 amino acids
Basic Information
3D PDB MODEL
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TPDB25418
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 21-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RWKRHISEQLRRRDRLQRQAX
Physicochemical Analysis
C113H194N48O29
NCGMFPTYV
R
2689.09
12.53
9
2
5
+6
9.29
-2.090
60.48
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
204.53
4
Residue Composition
number
1
A
7
R
0
N
1
D
0
C
1
E
3
Q
0
G
1
H
1
I
2
L
1
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 1 C: 0 E: 1 Q: 3 G: 0 H: 1 I: 1 L: 2 K: 1 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
21
C113H194N48O29
2689.09
12.53
+6
9.29
-2.090
Evidence Records 7 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
600 µM
Hemolytic Cytotoxic
0% Hemolysis | 600 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
500 µM
Hemolytic Cytotoxic
0% Hemolysis | 500 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 3 Activity

Activity

75% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
75% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 4 Activity

Activity

95% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
95% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 5 Activity

Activity

<5% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<5% Hemolysis | 200 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 6 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019
Evidence 7 Activity

Activity

10% Hemolysis
Toxicity
300 µM
Hemolytic Cytotoxic
10% Hemolysis | 300 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design, Synthesis, Antibacterial Potential, and Structural Characterization of N-Acylated Derivatives of the Human Autophagy 16 Polypeptide. | Bioconjug Chem | 2019