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Peptide record

TPDB25412

Antibacterial Anticancer Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB25412
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RWKIFKKIXKFLHSAKKF
Physicochemical Analysis
C110H173N29O19
NDCEQGMPTYV
K
2205.77
11.90
8
0
8
+7
1.25
-0.544
70.56
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
249.35
1
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
1
L
6
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 1 K: 6 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
18
C110H173N29O19
2205.77
11.90
+7
1.25
-0.544
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity. | Biochemistry | 2015
Evidence 2 Activity

Activity

50% Cell death
Toxicity
39 µM
Cytotoxic
50% Cell death | 39 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Peptoid-Substituted Hybrid Antimicrobial Peptide Derived from Papiliocin and Magainin 2 with Enhanced Bacterial Selectivity and Anti-inflammatory Activity. | Biochemistry | 2015