TPDB

3D PDB MODEL

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TPDB ID TPDB25405

Activity

Antibacterial Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia CAFPdb

Sequence_Type

modified_plain

Has_Modification Yes

Description A 38-aa modified multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.

Modification

Modified, details unspecified

Sequence

RWKFLKKIEKVGRKVRDGVIKAGPAVGVVGQATSIYKZ

FASTA

>TPDB25405|Antibacterial;Antifungal|length=38
RWKFLKKIEKVGRKVRDGVIKAGPAVGVVGQATSIYKZ

Formula C188H317N55O46

Absent Amino Acids NCHM

Common Amino Acids K

Mass 4083.93

PI 11.23

Basic Residues 10

Acidic Residues 2

Hydrophobic Residues 16

Net Charge +8

Boman Index 8.46

Hydrophobicity -0.208

Aliphatic Index 94.74

Half Life

Mammalian: 1 hour Yeast: 2 min E.coli: 2 min

Extinction Coefficient Cystines 6990

Absorbance 280nm 171.16

Polar Residues 4

number

3

A

3

R

0

N

1

D

0

C

1

E

1

Q

5

G

0

H

3

I

1

L

7

K

0

M

1

F

1

P

1

S

1

T

1

W

1

Y

6

V

Amino Acid Distribution

A: 3 R: 3 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 5 H: 0 I: 3 L: 1 K: 7 M: 0 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 1 V: 6

Length

38

Formula

C188H317N55O46

Mass

4083.93

PI

11.23

Net Charge

+8

Boman Index

8.46

Hydrophobicity

-0.208

Evidence 1 Activity

Source & Reference

Database Source CAFPdb