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Peptide record

TPDB25363

Antibacterial Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB25363
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 26-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RTKLWEMLVELGNMDKAVKLWRKLKR
Physicochemical Analysis
C147H249N43O35S2
CQHIFPSY
LK
3242.98
11.06
8
3
12
+5
6.23
-0.650
101.15
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
339.19
2
Residue Composition
number
1
A
3
R
1
N
1
D
0
C
2
E
0
Q
1
G
0
H
0
I
5
L
5
K
2
M
0
F
0
P
0
S
1
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 3 N: 1 D: 1 C: 0 E: 2 Q: 0 G: 1 H: 0 I: 0 L: 5 K: 5 M: 2 F: 0 P: 0 S: 0 T: 1 W: 2 Y: 0 V: 2
Chemical Descriptors
26
C147H249N43O35S2
3242.98
11.06
+5
6.23
-0.650
Evidence Records 1 records
Evidence 1 Activity

Activity

82% Cytotoxicity
Toxicity
50 µM
Cytotoxic
82% Cytotoxicity | 50 | µM | target cell: Murine macrophage cells IC-21

Target

Murine macrophage cells IC-21

Source & Reference

NA
DBAASP
New Antimicrobial Peptide with Two CRAC Motifs: Activity against Escherichia coli and Bacillus subtilis. | Microorganisms | 2022