Back to search

Peptide record

TPDB25351

Antibacterial Antifungal Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB25351
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RVCFRPVATYLGVCGVSGACRDHCVKLGSCVYKGPG
Physicochemical Analysis
C162H261N49O44S5
NEQIMW
GV
3759.46
8.80
6
1
13
+4
2.71
0.367
75.56
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
3230
85.92
10
Residue Composition
number
2
A
3
R
0
N
1
D
5
C
0
E
0
Q
6
G
1
H
0
I
2
L
2
K
0
M
1
F
2
P
2
S
1
T
0
W
2
Y
6
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 1 C: 5 E: 0 Q: 0 G: 6 H: 1 I: 0 L: 2 K: 2 M: 0 F: 1 P: 2 S: 2 T: 1 W: 0 Y: 2 V: 6
Chemical Descriptors
36
C162H261N49O44S5
3759.46
8.80
+4
2.71
0.367
Evidence Records 4 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, Characterization and Mode of Action of a Plant-Derived Antifungal Peptide, Cc-AFP1 Against Aspergillus Fumigatus | Research Square | 2021
Evidence 2 Activity

Activity

12.56% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
12.56% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Isolation, Characterization and Mode of Action of a Plant-Derived Antifungal Peptide, Cc-AFP1 Against Aspergillus Fumigatus | Research Square | 2021
Evidence 3 Activity

Activity

5% Killing
Toxicity
32 µg/mL
Cytotoxic
5% Killing | 32 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Isolation, Characterization and Mode of Action of a Plant-Derived Antifungal Peptide, Cc-AFP1 Against Aspergillus Fumigatus | Research Square | 2021
Evidence 4 Activity

Activity

10% Killing
Toxicity
128 µg/mL
Cytotoxic
10% Killing | 128 | µg/mL | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Isolation, Characterization and Mode of Action of a Plant-Derived Antifungal Peptide, Cc-AFP1 Against Aspergillus Fumigatus | Research Square | 2021