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Peptide record

TPDB25334

Antibacterial Toxicity standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB25334
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 14-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RTRTWRLALRWLKL
Physicochemical Analysis
C87H145N29O17
NDCEQGHIMFPSYV
RL
1869.29
12.88
5
0
7
+5
-1.60
-0.579
118.57
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
588.46
2
Residue Composition
number
1
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
1
K
0
M
0
F
0
P
0
S
2
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 1 M: 0 F: 0 P: 0 S: 0 T: 2 W: 2 Y: 0 V: 0
Chemical Descriptors
14
C87H145N29O17
1869.29
12.88
+5
-1.60
-0.579
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Hemolytic
NA | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides. | Adv Sci (Weinh) | 2022
Evidence 2 Activity

Activity

14% Cytotoxicity
Toxicity
640 µg/mL
Cytotoxic
14% Cytotoxicity | 640 | µg/mL | target cell: Human hepatocyte cells HL-7702 (L02)

Target

Human hepatocyte cells HL-7702 (L02)

Source & Reference

NA
DBAASP
Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides. | Adv Sci (Weinh) | 2022
Evidence 3 Activity

Activity

20% Cytotoxicity
Toxicity
640 µg/mL
Cytotoxic
20% Cytotoxicity | 640 | µg/mL | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Combating Escherichia coli O157:H7 with Functionalized Chickpea-Derived Antimicrobial Peptides. | Adv Sci (Weinh) | 2022