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Peptide record

TPDB25299

Antibacterial Anticancer Hemolysis Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB25299
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
RTHRAGLQFPVGRVHRLLRK
Physicochemical Analysis
C106H181N41O23
NDCEIMSWY
R
2397.86
13.00
8
0
7
+6
5.31
-0.750
92.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
2
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
1
Q
2
G
2
H
0
I
3
L
1
K
0
M
1
F
1
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 2 I: 0 L: 3 K: 1 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C106H181N41O23
2397.86
13.00
+6
5.31
-0.750
Evidence Records 3 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity. | Biochimie | 2015
Evidence 2 Activity

Activity

5.8±0.6% Hemolysis
Toxicity
32 µM
Hemolytic Cytotoxic
5.8±0.6% Hemolysis | 32 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hybrid peptide ATCUN-sh-Buforin: Influence of the ATCUN charge and stereochemistry on antimicrobial activity. | Biochimie | 2015
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis