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Peptide record

TPDB25290

Antibacterial Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB25290
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 51-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
RSQPGPTCPSSVQAILCDNRCGRSACSYYIERCACCAKCNRIPYYGASNHP
Physicochemical Analysis
C230H362N74O72S8
MFW
C
5572.34
8.31
7
2
14
+4
6.92
-0.461
46.08
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6460
115.93
24
Residue Composition
number
5
A
5
R
3
N
1
D
8
C
1
E
2
Q
3
G
1
H
3
I
1
L
1
K
0
M
0
F
5
P
6
S
1
T
0
W
4
Y
1
V
Amino Acid Distribution
A: 5 R: 5 N: 3 D: 1 C: 8 E: 1 Q: 2 G: 3 H: 1 I: 3 L: 1 K: 1 M: 0 F: 0 P: 5 S: 6 T: 1 W: 0 Y: 4 V: 1
Chemical Descriptors
51
C230H362N74O72S8
5572.34
8.31
+4
6.92
-0.461
Evidence Records 22 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>100 µM

Target

E.coli

Source & Reference

NA

Other

e against marine bacteria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
>100 µM

Target

P.aeruginosa

Source & Reference

NA

Other

ria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM),
Evidence 3 Activity

Activity

MIC
Antibacterial
100 µM

Target

Y. ruckeri

Source & Reference

NA

Other

tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum
Evidence 4 Activity

Activity

MIC
Antibacterial
50 µM

Target

L. anguillarum

Source & Reference

NA

Other

estrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC
Evidence 5 Activity

Activity

MIC
Antibacterial
100 µM

Target

A. salmonicida

Source & Reference

NA

Other

, P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum
Evidence 6 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C.glutamicum

Source & Reference

NA

Other

(MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. diver
Evidence 7 Activity

Activity

MIC
Antibacterial
>100 µM

Target

S.aureus

Source & Reference

NA

Other

m (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C.
Evidence 8 Activity

Activity

MIC
Antibacterial
25 µM

Target

C. maltaromaticum

Source & Reference

NA

Other

icida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It rema
Evidence 9 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C. mobile

Source & Reference

NA

Other

strial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether
Evidence 10 Activity

Activity

MIC
Antibacterial
25 µM

Target

C. divergens

Source & Reference

NA

Other

12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether the peptide is more active
Evidence 11 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C. funditum

Source & Reference

NA

Other

M), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether the peptide is more active at low temperature where the c
Evidence 12 Activity

Activity

MIC
Antifungal
>100 µM

Target

E.coli

Source & Reference

Antifungipept

Other

e against marine bacteria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM),
Evidence 13 Activity

Activity

MIC
Antifungal
>100 µM

Target

P.aeruginosa

Source & Reference

Antifungipept

Other

ria, but weakly in vitro. Activity tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM),
Evidence 14 Activity

Activity

MIC
Antifungal
100 µM

Target

Y. ruckeri

Source & Reference

Antifungipept

Other

tested against Gram- terrestrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum
Evidence 15 Activity

Activity

MIC
Antifungal
50 µM

Target

L. anguillarum

Source & Reference

Antifungipept

Other

estrial E.coli (MIC >100 uM), P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC
Evidence 16 Activity

Activity

MIC
Antifungal
100 µM

Target

A. salmonicida

Source & Reference

Antifungipept

Other

, P.aeruginosa (MIC >100 uM), marine Y. ruckeri (MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum
Evidence 17 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C.glutamicum

Source & Reference

Antifungipept

Other

(MIC 100 uM), L. anguillarum (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. diver
Evidence 18 Activity

Activity

MIC
Antifungal
>100 µM

Target

S.aureus

Source & Reference

Antifungipept

Other

m (MIC 50 uM), A. salmonicida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C.
Evidence 19 Activity

Activity

MIC
Antifungal
25 µM

Target

C. maltaromaticum

Source & Reference

Antifungipept

Other

icida (MIC 100 uM), Gram+ terrestrial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It rema
Evidence 20 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C. mobile

Source & Reference

Antifungipept

Other

strial C.glutamicum (MIC 12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether
Evidence 21 Activity

Activity

MIC
Antifungal
25 µM

Target

C. divergens

Source & Reference

Antifungipept

Other

12.5 uM), S.aureus (MIC >100 uM), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether the peptide is more active
Evidence 22 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C. funditum

Source & Reference

Antifungipept

Other

M), C. maltaromaticum (MIC 25 uM), C. mobile (MIC 12.5 uM), C. divergens (MIC 25 uM), and C. funditum (MIC 12.5 uM).It remains to be tested whether the peptide is more active at low temperature where the c