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Peptide record

TPDB25206

Antibacterial Anticancer Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB25206
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RRWLWRLRWLWR
Physicochemical Analysis
C92H135N31O13
ANDCEQGHIKMFPSTYV
R
1883.28
13.00
5
0
7
+5
-5.03
-1.225
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
22000
1168.17
0
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
12
C92H135N31O13
1883.28
13.00
+5
-5.03
-1.225
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
34 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 34 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design and Evaluation of Short Bovine Lactoferrin-Derived Antimicrobial Peptides against Multidrug-Resistant Enterococcus faecium. | Antibiotics (Basel) | 2022