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Peptide record

TPDB25197

Antibacterial Hemolysis Toxicity standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB25197
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia HemoPI PD_Hemolysis
standard
No
A 5-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, HemoPI, and PD_Hemolysis, with an available 3D structural model.
Sequence
RRWFW
Physicochemical Analysis
C43H55N13O6
ANDCEQGHILKMPSTYV
RW
849.99
12.40
2
0
3
+2
-3.21
-1.600
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
1294.13
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
5
C43H55N13O6
849.99
12.40
+2
-3.21
-1.600
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
10% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cyclic antimicrobial R-, W-rich peptides: the role of peptide structure and E. coli outer and inner membranes in activity and the mode of action. | Eur Biophys J | 2011
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis