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Peptide record

TPDB25179

Antibacterial Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB25179
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RRLXRRILRYL
Physicochemical Analysis
C63H115N25O12
ANDCEQGHKMFPSTWV
R
1414.77
12.58
5
0
5
+5
1.12
-0.718
141.82
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
105.32
1
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
11
C63H115N25O12
1414.77
12.58
+5
1.12
-0.718
Evidence Records 1 records
Evidence 1 Activity

Activity

100% Hemolysis
Toxicity
150 µM
Hemolytic Cytotoxic
100% Hemolysis | 150 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
An Amphipathic Undecapeptide With All d-Amino Acids Shows Promising Activity Against Colistin-Resistant Strains of Acinetobacter Baumannii and a Dual Mode of Action | Antimicrob Agents Chemother | 2015