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Peptide record

TPDB25093

Antibacterial Antifungal Toxicity standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB25093
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
standard
No
A 6-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Sequence
RRIWRR
Physicochemical Analysis
C41H71N19O7
ANDCEQGHLKMFPSTYV
R
942.14
12.88
4
0
2
+4
1.08
-2.400
65.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
583.78
0
Residue Composition
number
0
A
4
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
6
C41H71N19O7
942.14
12.88
+4
1.08
-2.400
Evidence Records 3 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, antimicrobial activity and mechanism of action of Arg-rich ultra-short cationic lipopeptides. | PLoS One | 2019
Evidence 2 Activity

Activity

60% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
60% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design, antimicrobial activity and mechanism of action of Arg-rich ultra-short cationic lipopeptides. | PLoS One | 2019
Evidence 3 Activity

Activity

0% Killing
Toxicity
100 µg/mL
Cytotoxic
0% Killing | 100 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Design, antimicrobial activity and mechanism of action of Arg-rich ultra-short cationic lipopeptides. | PLoS One | 2019