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Peptide record

TPDB25089

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB25089
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RRIRRPRLPRPRVPRPRIPPRI
Physicochemical Analysis
C124H224N52O23
ANDCEQGHKMFSTWY
R
2811.48
13.35
10
0
5
+10
9.83
-1.577
84.09
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
10
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
3
I
1
L
0
K
0
M
0
F
7
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 3 L: 1 K: 0 M: 0 F: 0 P: 7 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C124H224N52O23
2811.48
13.35
+10
9.83
-1.577
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
A Novel Proline-Rich Cathelicidin from the Alpaca Vicugna pacos with Potency to Combat Antibiotic-Resistant Bacteria: Mechanism of Action and the Functional Role of the C-Terminal Region | Membranes (Basel) | 2022
Evidence 2 Activity

Activity

0% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
0% Hemolysis | 128 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A Novel Proline-Rich Cathelicidin from the Alpaca Vicugna pacos with Potency to Combat Antibiotic-Resistant Bacteria: Mechanism of Action and the Functional Role of the C-Terminal Region | Membranes (Basel) | 2022