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Peptide record

TPDB25050

Antibacterial standard
105 amino acids
Basic Information
3D PDB MODEL
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TPDB25050
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 105-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RPTHCERWKGDKEYRCAKDNYRADSVTVRNRAGGTVSFKTGLWLSRCGHGGQNYGDHSYSLGPGGSQDVQFGEVGPGSCNEMFIYDCKINNRGANCLDAVNVQAN
Physicochemical Analysis
C488H747N155O157S7
G
11521.66
8.01
16
11
30
+2
23.22
-0.828
47.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
18825
163.39
35
Residue Composition
number
6
A
8
R
9
N
7
D
6
C
4
E
4
Q
15
G
3
H
2
I
4
L
5
K
1
M
3
F
3
P
7
S
4
T
2
W
5
Y
7
V
Amino Acid Distribution
A: 6 R: 8 N: 9 D: 7 C: 6 E: 4 Q: 4 G: 15 H: 3 I: 2 L: 4 K: 5 M: 1 F: 3 P: 3 S: 7 T: 4 W: 2 Y: 5 V: 7
Chemical Descriptors
105
C488H747N155O157S7
11521.66
8.01
+2
23.22
-0.828
Evidence Records 1 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

active against Gram-positive bacteria: B.subtilis (MIC 100–1000 ug/ml), M. luteus (MIC 1–10 ug/ml), and S. aureus (MIC 10–100 µg/ml), but not against Gram-negative bacteria (E.coli, E.cloacae, Pantoea sp., the gut symbiont of P.stal, MIC >1000 ug/ml i) and Gram+ (E. faecalis and E.faecium, MIC >1000 ug/ml).