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Peptide record

TPDB25022

Antibacterial Antifungal standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB25022
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 38-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
RPQFFEAVGDFVENVGEGVGDFFEGVGDFFSNVFSGSS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C187H256N44O60
CHILKMTWY
F
4080.35
3.32
1
7
15
-6
1.17
0.061
48.42
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
7
Residue Composition
number
1
A
1
R
2
N
3
D
0
C
4
E
1
Q
7
G
0
H
0
I
0
L
0
K
0
M
8
F
1
P
4
S
0
T
0
W
0
Y
6
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 3 C: 0 E: 4 Q: 1 G: 7 H: 0 I: 0 L: 0 K: 0 M: 0 F: 8 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 6
Chemical Descriptors
38 reviewed residue count
C187H256N44O60 sequence-only estimate (linear, free termini)
4080.35 sequence-only estimate (linear, free termini)
3.32 sequence-only estimate (linear, free termini)
-6 sequence-only estimate (linear, free termini)
1.17 sequence-only estimate (linear, free termini)
0.061 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against both Gram+ S. aureus, M. luteus, and Gram- bacteira E. coli.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against both Gram+ S. aureus, M. luteus, and Gram- bacteira E. coli.