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Peptide record

TPDB24981

Antibacterial Antifungal standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB24981
Antibacterial Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RLRAPPPFHKRCVCLCRTAPPP
Physicochemical Analysis
C111H183N37O24S3
NDEQGIMSWY
P
2516.09
11.16
6
0
6
+5
4.79
-0.441
57.73
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
4.97
4
Residue Composition
number
2
A
4
R
0
N
0
D
3
C
0
E
0
Q
0
G
1
H
0
I
2
L
1
K
0
M
1
F
6
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 3 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 2 K: 1 M: 0 F: 1 P: 6 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
22
C111H183N37O24S3
2516.09
11.16
+5
4.79
-0.441
Evidence Records 16 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6-12 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epi
Evidence 2 Activity

Activity

MIC
Antibacterial
3-6 µM

Target

L. monocytogenes

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P
Evidence 3 Activity

Activity

MIC
Antibacterial
3-6 µM

Target

Enterococcus faecalis

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM)
Evidence 4 Activity

Activity

MIC
Antibacterial
3-6 µM

Target

E. faecium

Source & Reference

NA

Other

t Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM),
Evidence 5 Activity

Activity

MIC
Antibacterial
6-12 µM

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), f
Evidence 6 Activity

Activity

MIC
Antibacterial
6-12 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F.
Evidence 7 Activity

Activity

MIC
Antibacterial
6-12 µM

Target

Escherichia coli

Source & Reference

NA

Other

E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F. graminearum (MFC 12-24
Evidence 8 Activity

Activity

MIC
Antibacterial
6-12 µM

Target

A. baunmannii

Source & Reference

NA

Other

, S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F. graminearum (MFC 12-24 uM), F. solani (MFC 12-24 uM
Evidence 9 Activity

Activity

MIC
Antifungal
6-12 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epi
Evidence 10 Activity

Activity

MIC
Antifungal
3-6 µM

Target

L. monocytogenes

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P
Evidence 11 Activity

Activity

MIC
Antifungal
3-6 µM

Target

Enterococcus faecalis

Source & Reference

NA

Other

active against Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM)
Evidence 12 Activity

Activity

MIC
Antifungal
3-6 µM

Target

E. faecium

Source & Reference

NA

Other

t Gram+ S. aureus (MIC 6-12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM),
Evidence 13 Activity

Activity

MIC
Antifungal
6-12 µM

Target

Staphylococcus epidermidis

Source & Reference

NA

Other

12 uM), L. monocytogenes (MIC 3-6 uM), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), f
Evidence 14 Activity

Activity

MIC
Antifungal
6-12 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

), E. faecalis (MIC 3-6 uM), E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F.
Evidence 15 Activity

Activity

MIC
Antifungal
6-12 µM

Target

Escherichia coli

Source & Reference

NA

Other

E. faecium (MIC 3-6 uM), S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F. graminearum (MFC 12-24
Evidence 16 Activity

Activity

MIC
Antifungal
6-12 µM

Target

A. baunmannii

Source & Reference

NA

Other

, S. epidermidis (MIC 6-12 uM), Gram- P. aeruginosa (MIC 6-12 uM), E. coli (MIC 6-12 uM), A. baunmannii (MIC 6-12 uM), fungi C. neoformans (MFC 3-6 uM), F. graminearum (MFC 12-24 uM), F. solani (MFC 12-24 uM