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Peptide record

TPDB24952

Antibacterial Toxicity standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB24952
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 16-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RLFRRVKKVAGKIAKR
Physicochemical Analysis
C87H160N32O17
NDCEQHMPSTWY
RK
1926.43
12.89
8
0
7
+8
5.01
-0.681
97.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
4
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 4 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
16
C87H160N32O17
1926.43
12.89
+8
5.01
-0.681
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>250 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | >250 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel D-form of hybrid peptide (D-AP19) rapidly kills Acinetobacter baumannii while tolerating proteolytic enzymes. | Sci Rep | 2022