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Peptide record

TPDB24884

Antibacterial Anticancer Antifungal Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB24884
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RKKAIKLVKKLVKKLKKALK
Physicochemical Analysis
C112H217N33O21
NDCEQGHMFPSTWY
K
2362.16
12.02
11
0
9
+11
7.96
-0.590
136.50
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
4
L
10
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 4 K: 10 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C112H217N33O21
2362.16
12.02
+11
7.96
-0.590
Evidence Records 3 records
Evidence 1 Activity

Activity

20% Killing
Toxicity
128 µg/mL
Cytotoxic
20% Killing | 128 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Ω76: A designed antimicrobial peptide to combat carbapenem- and tigecycline-resistant Acinetobacter baumannii. | Sci Adv | 2019
Evidence 2 Activity

Activity

13.91% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
13.91% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Ω76: A designed antimicrobial peptide to combat carbapenem- and tigecycline-resistant Acinetobacter baumannii. | Sci Adv | 2019
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Sci Adv. 2019 Jul 24 5(7):eaax1946.