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Peptide record

TPDB24850

Antibacterial Toxicity modified_plain modified
24 amino acids
Basic Information
3D PDB MODEL
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TPDB24850
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 24-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
RIIDRLWRVRRPQKPKFVIVWVRX
Physicochemical Analysis
C142H234N46O27
ANCEGHMSTY
R
3017.71
12.71
8
1
11
+7
3.51
-0.412
113.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
364.51
1
Residue Composition
number
0
A
6
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
3
I
1
L
2
K
0
M
1
F
2
P
0
S
0
T
2
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 3 L: 1 K: 2 M: 0 F: 1 P: 2 S: 0 T: 0 W: 2 Y: 0 V: 4
Chemical Descriptors
24
C142H234N46O27
3017.71
12.71
+7
3.51
-0.412
Evidence Records 2 records
Evidence 1 Activity

Activity

<4% Hemolysis
Toxicity
1280 µg/mL
Hemolytic Cytotoxic
<4% Hemolysis | 1280 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Decanoic acid modification enhances the antibacterial activity of PMAP-23RI-Dec | Eur J Pharm Sci | 2020
Evidence 2 Activity

Activity

<20% Killing
Toxicity
1280 µg/mL
Cytotoxic
<20% Killing | 1280 | µg/mL | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Decanoic acid modification enhances the antibacterial activity of PMAP-23RI-Dec | Eur J Pharm Sci | 2020