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Peptide record

TPDB24825

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
47 amino acids
Basic Information
3D PDB MODEL
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TPDB24825
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 47-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RICRRRSAGFKGPCVSNKNCAQVCMQEGWGGGNCDGPLRRCKCMRRC
Physicochemical Analysis
C209H352N80O59S10
HTY
RC
5250.19
9.88
11
2
10
+9
9.92
-0.719
33.19
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6000
114.28
15
Residue Composition
number
2
A
8
R
3
N
1
D
8
C
1
E
2
Q
7
G
0
H
1
I
1
L
3
K
2
M
1
F
2
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 8 N: 3 D: 1 C: 8 E: 1 Q: 2 G: 7 H: 0 I: 1 L: 1 K: 3 M: 2 F: 1 P: 2 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
47
C209H352N80O59S10
5250.19
9.88
+9
9.92
-0.719
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
400 µg/mL
Hemolytic Cytotoxic
<10% Hemolysis | 400 | µg/mL | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Study on the Inhibitory Activity of a Synthetic Defensin Derived from Barley Endosperm against Common Food Spoilage Yeast. | Molecules | 2020