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Peptide record

TPDB24815

Antibacterial Antifungal standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB24815
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 51-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RHRHCFSQSHKFVGACLRESNCENVCKTEGFPSGECKWHGIVSKCHCKRIC
Physicochemical Analysis
C247H386N82O69S8
DMY
C
5864.77
8.53
14
4
11
+5
15.47
-0.612
41.96
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
6000
102.31
17
Residue Composition
number
1
A
4
R
2
N
0
D
8
C
4
E
1
Q
4
G
5
H
2
I
1
L
5
K
0
M
3
F
1
P
5
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 0 C: 8 E: 4 Q: 1 G: 4 H: 5 I: 2 L: 1 K: 5 M: 0 F: 3 P: 1 S: 5 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
51
C247H386N82O69S8
5864.77
8.53
+5
15.47
-0.612
Evidence Records 4 records
Evidence 1 Activity

Activity

IC50
Antibacterial
3.5 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungi such as Active against fungi such as N. crassa (IC50 3.5 uM), A. niger (IC50 1.0 uM), and F-solani (IC50 >20 uM).
Evidence 2 Activity

Activity

IC50
Antibacterial
1.0 µM

Target

A. niger

Source & Reference

dbAMP DRAMP

Other

Active against fungi such as Active against fungi such as N. crassa (IC50 3.5 uM), A. niger (IC50 1.0 uM), and F-solani (IC50 >20 uM).
Evidence 3 Activity

Activity

IC50
Antifungal
3.5 µM

Target

N. crassa

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against fungi such as Active against fungi such as N. crassa (IC50 3.5 uM), A. niger (IC50 1.0 uM), and F-solani (IC50 >20 uM).
Evidence 4 Activity

Activity

IC50
Antifungal
1.0 µM

Target

A. niger

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against fungi such as Active against fungi such as N. crassa (IC50 3.5 uM), A. niger (IC50 1.0 uM), and F-solani (IC50 >20 uM).