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Peptide record

TPDB24778

Antibacterial Antifungal Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB24778
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
RGGRLXYCRRRFCVXVGR
Physicochemical Analysis
C82H140N34O18S2
ANDEQHIKMPSTW
R
1954.35
12.10
6
0
5
+6
1.92
-0.528
53.89
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1615
82.64
3
Residue Composition
number
0
A
6
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
18
C82H140N34O18S2
1954.35
12.10
+6
1.92
-0.528
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
74.6 µM
Hemolytic Cytotoxic
50% Hemolysis | 74.6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic selectivity of cystine-stabilized cyclic protegrins. | Eur J Biochem | 2000
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
129.8 µM
Hemolytic Cytotoxic
50% Hemolysis | 129.8 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic selectivity of cystine-stabilized cyclic protegrins. | Eur J Biochem | 2000