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Peptide record

TPDB24761

Antibacterial Toxicity standard
59 amino acids
Basic Information
3D PDB MODEL
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TPDB24761
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 59-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RGLRRLGRKIAHGVKKYGPTVLRIIRIAGGGGGSHVDKKVADKVLLLKQLRIMRLLTRL
Physicochemical Analysis
C293H522N98O69S1
NCEFW
L
6554.04
12.51
18
2
25
+14
11.65
-0.078
128.81
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
22.73
5
Residue Composition
number
3
A
9
R
0
N
2
D
0
C
0
E
1
Q
9
G
2
H
5
I
10
L
7
K
1
M
0
F
1
P
1
S
2
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 3 R: 9 N: 0 D: 2 C: 0 E: 0 Q: 1 G: 9 H: 2 I: 5 L: 10 K: 7 M: 1 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 1 V: 5
Chemical Descriptors
59
C293H522N98O69S1
6554.04
12.51
+14
11.65
-0.078
Evidence Records 1 records
Evidence 1 Activity

Activity

83% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
83% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011