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Peptide record

TPDB24760

Antibacterial Toxicity standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB24760
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 57-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RGLRRLGRKIAHGVKKYGPTVLRIIRIAGEKRHVDKKVADKVLLLKQLRIMRLLTRL
Physicochemical Analysis
C299H536N100O68S1
NCFSW
RL
6652.23
12.42
20
3
25
+15
15.30
-0.247
133.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
22.40
4
Residue Composition
number
3
A
10
R
0
N
2
D
0
C
1
E
1
Q
5
G
2
H
5
I
10
L
8
K
1
M
0
F
1
P
0
S
2
T
0
W
1
Y
5
V
Amino Acid Distribution
A: 3 R: 10 N: 0 D: 2 C: 0 E: 1 Q: 1 G: 5 H: 2 I: 5 L: 10 K: 8 M: 1 F: 0 P: 1 S: 0 T: 2 W: 0 Y: 1 V: 5
Chemical Descriptors
57
C299H536N100O68S1
6652.23
12.42
+15
15.30
-0.247
Evidence Records 1 records
Evidence 1 Activity

Activity

84% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
84% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent antimicrobial peptides with selectivity for Bacillus anthracis over human erythrocytes. | Int J Antimicrob Agents | 2011