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Peptide record

TPDB24758

Antibacterial Antifungal Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB24758
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
RGGRLXYXRRRFXVCXGR
Physicochemical Analysis
C74H126N32O16S1
ANDEQHIKMPSTW
R
1752.08
12.40
6
0
4
+6
2.09
-0.900
37.78
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
85.04
2
Residue Composition
number
0
A
6
R
0
N
0
D
1
C
0
E
0
Q
3
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C74H126N32O16S1
1752.08
12.40
+6
2.09
-0.900
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
112.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 112.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic selectivity of cystine-stabilized cyclic protegrins. | Eur J Biochem | 2000