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Peptide record

TPDB24745

Antibacterial Antifungal standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB24745
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
RGCYTRCWKVGRNGRVCMRVCT
Physicochemical Analysis
C106H178N40O27S5
ADEQHILFPS
R
2605.13
10.41
6
0
6
+6
2.00
-0.464
39.55
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
7240
277.91
8
Residue Composition
number
0
A
5
R
1
N
0
D
4
C
0
E
0
Q
3
G
0
H
0
I
0
L
1
K
1
M
0
F
0
P
0
S
2
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 0 C: 4 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 1 M: 1 F: 0 P: 0 S: 0 T: 2 W: 1 Y: 1 V: 3
Chemical Descriptors
22
C106H178N40O27S5
2605.13
10.41
+6
2.00
-0.464
Evidence Records 2 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.012-0.096 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

eudomonas sp.*, V. diabolicus, Vibrio MPV19 (MIC 0.012-0.096uM), Gram+ B. megaterium, and S. aureus (MIC 0.012-0.096 uM). This marine peptide has a very low MIC below 100 nM and its activity is salt-insensitive
Evidence 2 Activity

Activity

MIC
Antifungal
0.012-0.096 µM

Target

Staphylococcus aureus

Source & Reference

Antifungipept

Other

eudomonas sp.*, V. diabolicus, Vibrio MPV19 (MIC 0.012-0.096uM), Gram+ B. megaterium, and S. aureus (MIC 0.012-0.096 uM). This marine peptide has a very low MIC below 100 nM and its activity is salt-insensitive