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Peptide record

TPDB24742

Antibacterial Antifungal Toxicity modified_plain modified
18 amino acids
Basic Information
3D PDB MODEL
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TPDB24742
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 18-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
RGGCLXYCRRRFCVXVCR
Physicochemical Analysis
C80H135N31O18S4
ANDEQHIKMPSTW
R
1947.39
9.95
5
0
5
+5
0.62
0.022
53.89
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1740
89.35
5
Residue Composition
number
0
A
5
R
0
N
0
D
4
C
0
E
0
Q
2
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
18
C80H135N31O18S4
1947.39
9.95
+5
0.62
0.022
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
123.2 µM
Hemolytic Cytotoxic
50% Hemolysis | 123.2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Membranolytic selectivity of cystine-stabilized cyclic protegrins. | Eur J Biochem | 2000