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Peptide record

TPDB24730

Antibacterial Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB24730
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RGLFKKLLRKIKKGFKK
Physicochemical Analysis
C100H178N30O18
ANDCEQHMPSTWYV
K
2088.70
12.47
9
0
6
+9
4.32
-0.918
91.76
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
3
L
7
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 3 K: 7 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C100H178N30O18
2088.70
12.47
+9
4.32
-0.918
Evidence Records 2 records
Evidence 1 Activity

Activity

55% Cell death
Toxicity
200 µg/mL
Cytotoxic
55% Cell death | 200 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Hydrophobicity Determines the Bacterial Killing Rate of α-Helical Antimicrobial Peptides and Influences the Bacterial Resistance Development. | J Med Chem | 2022
Evidence 2 Activity

Activity

22% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
22% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Hydrophobicity Determines the Bacterial Killing Rate of α-Helical Antimicrobial Peptides and Influences the Bacterial Resistance Development. | J Med Chem | 2022