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Peptide record

TPDB24584

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB24584
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
RALRRLARKIAHAVKKYG
Physicochemical Analysis
C94H167N35O20
NDCEQMFPSTW
AR
2107.58
12.42
8
0
9
+7
4.20
-0.617
103.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
70.70
1
Residue Composition
number
4
A
4
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
1
I
2
L
3
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 4 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 1 L: 2 K: 3 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C94H167N35O20
2107.58
12.42
+7
4.20
-0.617
Evidence Records 1 records
Evidence 1 Activity

Activity

2% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
2% Hemolysis | 100 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
Discovery of structural and functional transition sites for membrane-penetrating activity of sheep myeloid antimicrobial peptide-18. | Sci Rep | 2023