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Peptide record

TPDB24560

Antibacterial Antifungal Toxicity standard
98 amino acids
Basic Information
3D PDB MODEL
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TPDB24560
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 98-aa standard-residue multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
QVLEGLAAAVTGKLAGLWRNGEVELLGHYCSYSVTPTIRRWQLYFRGRMWCPGWTSIRGEAMTRSNSGVQGDTTRDFVTKALNAGLISQQEAQAWLDG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C480H746N140O141S4
G
10862.30
8.93
11
8
40
+2
1.52
-0.265
78.67
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
32095
2.95
28
Residue Composition
number
9
A
8
R
3
N
3
D
2
C
5
E
6
Q
12
G
1
H
3
I
10
L
2
K
2
M
2
F
2
P
6
S
8
T
5
W
3
Y
6
V
Amino Acid Distribution
A: 9 R: 8 N: 3 D: 3 C: 2 E: 5 Q: 6 G: 12 H: 1 I: 3 L: 10 K: 2 M: 2 F: 2 P: 2 S: 6 T: 8 W: 5 Y: 3 V: 6
Chemical Descriptors
98 reviewed residue count
C480H746N140O141S4 sequence-only estimate (linear, free termini)
10862.30 sequence-only estimate (linear, free termini)
8.93 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.52 sequence-only estimate (linear, free termini)
-0.265 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against G+ bacteria S. aureus, B. subtilis, B. cereus, B. thuringiensis, and B. megaterium, G- bacteria E. coli and P. aeruginosa, including V. anguillarum, and fungi C. albicans. Recombinant PcALF1 can clear fish pathogen V. anguillarum.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against G+ bacteria S. aureus, B. subtilis, B. cereus, B. thuringiensis, and B. megaterium, G- bacteria E. coli and P. aeruginosa, including V. anguillarum, and fungi C. albicans. Recombinant PcALF1 can clear fish pathogen V. anguillarum.