Back to search

Peptide record

TPDB24512

Antibacterial Antifungal standard
120 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB24512
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 120-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
QNERYEKFLRQHYDAKPNGRDDRYCESMMKERKLTSPCKDVNTFIHGTKKNIRAICGKKGSPYGENFRISNSPFQITTCTHSGASPRPPCGYRAFKDFRYIVIACEDGWPVHFDESFISP
Physicochemical Analysis
C613H934N178O179S8
RK
13917.73
9.03
24
14
35
+6
32.32
-0.905
43.92
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
14815
106.45
36
Residue Composition
number
5
A
10
R
6
N
7
D
6
C
7
E
3
Q
8
G
4
H
8
I
2
L
10
K
2
M
8
F
9
P
9
S
6
T
1
W
6
Y
3
V
Amino Acid Distribution
A: 5 R: 10 N: 6 D: 7 C: 6 E: 7 Q: 3 G: 8 H: 4 I: 8 L: 2 K: 10 M: 2 F: 8 P: 9 S: 9 T: 6 W: 1 Y: 6 V: 3
Chemical Descriptors
120
C613H934N178O179S8
13917.73
9.03
+6
32.32
-0.905
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. faecalis, L. monocytogenes (both Gram-positive pathogens declined by >99% after a 2 h exposure to 1 uM of Ang4). Inhibited intestinal commensal Gram- B. thetaiotaomicron by 30% (1 uM). No effect on E-coli K12 and L-innocua (at 10 uM). Also angiogenic with RNase activity.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against E. faecalis, L. monocytogenes (both Gram-positive pathogens declined by >99% after a 2 h exposure to 1 uM of Ang4). Inhibited intestinal commensal Gram- B. thetaiotaomicron by 30% (1 uM). No effect on E-coli K12 and L-innocua (at 10 uM). Also angiogenic with RNase activity.