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Peptide record

TPDB24511

Antibacterial Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB24511
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 57-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
QNCPTRRGLCVTSGLTACRNHCRSCHRGDVGCVRCSNAQCTGFLGTTCTCINPCPRC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C238H398N88O76S12
EKMWY
C
6093.04
8.33
9
1
10
+6
2.26
-0.211
46.14
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
750
0.12
28
Residue Composition
number
2
A
7
R
4
N
1
D
12
C
0
E
2
Q
6
G
2
H
1
I
3
L
0
K
0
M
1
F
3
P
3
S
7
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 2 R: 7 N: 4 D: 1 C: 12 E: 0 Q: 2 G: 6 H: 2 I: 1 L: 3 K: 0 M: 0 F: 1 P: 3 S: 3 T: 7 W: 0 Y: 0 V: 3
Chemical Descriptors
57 reviewed residue count
C238H398N88O76S12 sequence-only estimate (linear, free termini)
6093.04 sequence-only estimate (linear, free termini)
8.33 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
2.26 sequence-only estimate (linear, free termini)
-0.211 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against B. subtilis 168 S. pneumoniae, S. pyogenes, S. carnosus, S. epidermidis, L. monocytogenes WSLC 1042 or 1001, L. ivanovii WSLC 3009 or 2012, E. faecium DSM 20477, E. faecium VRE DSM 13590 (anti-VRE), E. faecalis DSM 20478, M. luteus, C. diphtheriae.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against B. subtilis 168 S. pneumoniae, S. pyogenes, S. carnosus, S. epidermidis, L. monocytogenes WSLC 1042 or 1001, L. ivanovii WSLC 3009 or 2012, E. faecium DSM 20477, E. faecium VRE DSM 13590 (anti-VRE), E. faecalis DSM 20478, M. luteus, C. diphtheriae.