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Peptide record

TPDB24509

Antibacterial Antifungal standard
117 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB24509
Antibacterial Antifungal
Anti-infective peptides
Peptipedia
standard
No
A 117-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QNKDDTRFLGGVPGVGGGFVPGVPGHGGVAPVGGGLVPGGGGLIPGGGFECNYCRTRYYVCCKPGRRCPPVRDVCPGLRQGVPICRQDTDCFGSDKCCYDVCLNDTVCKPIVLGSEG
Physicochemical Analysis
C516H811N153O154S12
MW
G
12006.77
7.63
13
10
32
+2
20.12
-0.102
65.56
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
6710
55.89
28
Residue Composition
number
1
A
8
R
3
N
8
D
12
C
2
E
3
Q
26
G
1
H
3
I
6
L
4
K
0
M
4
F
12
P
2
S
4
T
0
W
4
Y
14
V
Amino Acid Distribution
A: 1 R: 8 N: 3 D: 8 C: 12 E: 2 Q: 3 G: 26 H: 1 I: 3 L: 6 K: 4 M: 0 F: 4 P: 12 S: 2 T: 4 W: 0 Y: 4 V: 14
Chemical Descriptors
117
C516H811N153O154S12
12006.77
7.63
+2
20.12
-0.102
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E.
Evidence 3 Activity

Activity

MIC
Antibacterial
4 µM

Target

M. luteus

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. a
Evidence 4 Activity

Activity

MIC
Antibacterial
2 µM

Target

B. megaterium

Source & Reference

NA

Other

gainst Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-
Evidence 5 Activity

Activity

MIC
Antibacterial
4 µM

Target

B. cereus

Source & Reference

NA

Other

ureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM),
Evidence 6 Activity

Activity

MIC
Antibacterial
32 µM

Target

Escherichia coli

Source & Reference

NA

Other

uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrop
Evidence 7 Activity

Activity

MIC
Antibacterial
32 µM

Target

V. anguillarum

Source & Reference

NA

Other

uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. n
Evidence 8 Activity

Activity

MIC
Antibacterial
16 µM

Target

A. hydrophila

Source & Reference

NA

Other

IC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. niger and R. oryzae (MIC 32 uM).
Evidence 9 Activity

Activity

MIC
Antibacterial
32 µM

Target

R. oryzae

Source & Reference

NA

Other

yi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. niger and R. oryzae (MIC 32 uM).
Evidence 10 Activity

Activity

MIC
Antifungal
2 µM

Target

Staphylococcus aureus

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4
Evidence 11 Activity

Activity

MIC
Antifungal
8 µM

Target

B. subtilis

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E.
Evidence 12 Activity

Activity

MIC
Antifungal
4 µM

Target

M. luteus

Source & Reference

NA

Other

Active against Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. a
Evidence 13 Activity

Activity

MIC
Antifungal
2 µM

Target

B. megaterium

Source & Reference

NA

Other

gainst Gram+ bacteria S. aureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-
Evidence 14 Activity

Activity

MIC
Antifungal
4 µM

Target

B. cereus

Source & Reference

NA

Other

ureus (MIC 2 uM), B. subtilis (MIC 8 uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM),
Evidence 15 Activity

Activity

MIC
Antifungal
32 µM

Target

Escherichia coli

Source & Reference

NA

Other

uM), M. luteus (MIC 4 uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrop
Evidence 16 Activity

Activity

MIC
Antifungal
32 µM

Target

V. anguillarum

Source & Reference

NA

Other

uM), B. megaterium (MIC 2 uM), B. cereus (MIC 4 uM), Gram- bacteria E. coli (MIC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. n
Evidence 17 Activity

Activity

MIC
Antifungal
16 µM

Target

A. hydrophila

Source & Reference

NA

Other

IC 32 uM), V. anguillarum (MIC 32 uM), V-Harveyi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. niger and R. oryzae (MIC 32 uM).
Evidence 18 Activity

Activity

MIC
Antifungal
32 µM

Target

R. oryzae

Source & Reference

NA

Other

yi (MIC >64 uM), (MIC 2 uM), K. pneumoniae, A. hydrophila (MIC 16 uM), fungi A. niger and R. oryzae (MIC 32 uM).