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Peptide record

TPDB24494

Antibacterial Anticancer Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB24494
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia and PD_Hemolysis, with an available 3D structural model.
Sequence
QIWHKIRKLWQIIKDGF
Physicochemical Analysis
C107H165N29O22
ANCEMPSTYV
I
2209.67
10.83
5
1
8
+3
0.51
-0.441
114.71
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
11000
497.81
2
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
0
E
2
Q
1
G
1
H
4
I
1
L
3
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 0 Q: 2 G: 1 H: 1 I: 4 L: 1 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
17
C107H165N29O22
2209.67
10.83
+3
0.51
-0.441
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
23±5 µM
Hemolytic Cytotoxic
50% Hemolysis | 23±5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Designing Anticancer Peptides by Constructive Machine Learning. | ChemMedChem | 2018
Evidence 2 Activity

Activity

% Hemolysis
Toxicity
50 %
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: 50% Hemolysis=23±5 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
ChemMedChem. 2018 Jul 6 13(13):1300-1302.
Evidence 3 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis