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Peptide record

TPDB24430

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB24430
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QHARKKKKRAHQ
Physicochemical Analysis
C64H114N28O15
NDCEGILMFPSTWYV
K
1515.79
12.44
8
0
2
+6
8.32
-2.867
16.67
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
0
E
2
Q
0
G
2
H
0
I
0
L
4
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 2 I: 0 L: 0 K: 4 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C64H114N28O15
1515.79
12.44
+6
8.32
-2.867
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
375.53 ± 26.12 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 375.53 ± 26.12 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design, synthesis, antifungal evaluation and docking studies of antifungal peptide CGA-N12 analogues based on the target CtKRE9. | Bioorg Chem | 2023