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Peptide record

TPDB24423

Antibacterial standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB24423
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 32-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QETLDPICMAKCVLKCGKKAWCLTKCIAGCVL
Physicochemical Analysis
C150H257N39O40S7
RNHFSY
C
3471.35
8.31
5
2
13
+3
2.78
0.631
100.63
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
5875
169.24
9
Residue Composition
number
3
A
0
R
0
N
1
D
6
C
1
E
1
Q
2
G
0
H
2
I
4
L
5
K
1
M
0
F
1
P
0
S
2
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 6 E: 1 Q: 1 G: 2 H: 0 I: 2 L: 4 K: 5 M: 1 F: 0 P: 1 S: 0 T: 2 W: 1 Y: 0 V: 2
Chemical Descriptors
32
C150H257N39O40S7
3471.35
8.31
+3
2.78
0.631
Evidence Records 5 records
Evidence 1 Activity

Activity

IC50
Antibacterial
14.5 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

IC50: 50% inhibition concentration: Gram- E. coli ATCC 25922 (IC50 14.5 uM), K. pneumoniae VK148 (IC50 13.2 uM), A. baumannii 5075 (IC50 4.0 uM), and P. aeruginosa 1
Evidence 2 Activity

Activity

IC50
Antibacterial
13.2 µM

Target

Klebsiella pneumoniae VK148

Source & Reference

NA

Other

IC50: 50% inhibition concentration: Gram- E. coli ATCC 25922 (IC50 14.5 uM), K. pneumoniae VK148 (IC50 13.2 uM), A. baumannii 5075 (IC50 4.0 uM), and P. aeruginosa 1423 (IC50 6.9 uM). Bactericidal: MBC
Evidence 3 Activity

Activity

IC50
Antibacterial
4.0 µM

Target

A. baumannii 5075

Source & Reference

NA

Other

ncentration: Gram- E. coli ATCC 25922 (IC50 14.5 uM), K. pneumoniae VK148 (IC50 13.2 uM), A. baumannii 5075 (IC50 4.0 uM), and P. aeruginosa 1423 (IC50 6.9 uM). Bactericidal: MBC against A. baumannii 5075 (IC50
Evidence 4 Activity

Activity

IC50
Antibacterial
6.9 µM

Target

Pseudomonas aeruginosa 1423

Source & Reference

NA

Other

(IC50 14.5 uM), K. pneumoniae VK148 (IC50 13.2 uM), A. baumannii 5075 (IC50 4.0 uM), and P. aeruginosa 1423 (IC50 6.9 uM). Bactericidal: MBC against A. baumannii 5075 (IC50 8.6 uM).
Evidence 5 Activity

Activity

IC50
Antibacterial
8.6 µM

Target

A. baumannii 5075

Source & Reference

NA

Other

annii 5075 (IC50 4.0 uM), and P. aeruginosa 1423 (IC50 6.9 uM). Bactericidal: MBC against A. baumannii 5075 (IC50 8.6 uM).