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Peptide record

TPDB24417

Antibacterial Anticancer Antifungal Toxicity standard
62 amino acids
Basic Information
3D PDB MODEL
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TPDB24417
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 62-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
QFNMQGGGSPRQGFDVNANARFPIWQSQNARNSVHGTASYAQHLGGPYGNSRPNFGGGLQFT
Physicochemical Analysis
C290H425N93O88S1
CEK
G
6654.19
11.12
6
1
19
+3
4.48
-0.826
36.29
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
8480
127.44
23
Residue Composition
number
5
A
4
R
7
N
1
D
0
C
0
E
7
Q
11
G
2
H
1
I
2
L
0
K
1
M
5
F
4
P
5
S
2
T
1
W
2
Y
2
V
Amino Acid Distribution
A: 5 R: 4 N: 7 D: 1 C: 0 E: 0 Q: 7 G: 11 H: 2 I: 1 L: 2 K: 0 M: 1 F: 5 P: 4 S: 5 T: 2 W: 1 Y: 2 V: 2
Chemical Descriptors
62
C290H425N93O88S1
6654.19
11.12
+3
4.48
-0.826
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
64 µg/mL

Target

M. smegmatis ATCC 607

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Among the panel of bacteria, only active against M. smegmatis ATCC 607 (MIC 64 µg/mL)
Evidence 2 Activity

Activity

MIC
Antifungal
64 µg/mL

Target

M. smegmatis ATCC 607

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Among the panel of bacteria, only active against M. smegmatis ATCC 607 (MIC 64 µg/mL)
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides from Rat-Tailed Maggots of the Drone Fly Eristalis tenax Show Potent Activity against Multidrug-Resistant Gram-Negative Bacteria. | Microorganisms | 2020
Evidence 4 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: Not active up to 1024 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Microorganisms. 2020 Apr 25 8(5):626